General introduction: Public health and hygiene, human reproductive system, sex and sexuality. History of sexually transmitted diseases (STDs); History of Human Immunodeficiency virus/Acquired Immune deficiency Syndrome (HIV/AIDS), Comparative information on trends, global and local distribution, Justification of importance of course. Biology of HIV/AIDS; Overview of immune system, natural immunity to HIV/AIDS. The AIDS virus and its life cycle, disease progression, transmission and diagnosis. Discordant couples. Treatment and Management; nutrition, prevention and control; Abstain, Be faithful, Condom use, Destigmatize HIV/AIDS (ABCD) methods