STAGES OF PRENATAL DEVELOPMENT

Institution TVET
Course DIPLOMA IN SOCIAL WO...
Year 1st Year
Semester Unknown
Posted By stephen oyake rabilo
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The human life cycle may be said to begin with fertilization and then proceed through prenatal growth and development, birth, postnatal growth and development, maturity, senescence, and death. While you might think of child development as something that begins during infancy, the prenatal period is also considered an important part of the developmental process. Prenatal development is a time of remarkable change that helps set the stage for future psychological development. The brain develops over the course of the prenatal period, but it will continue to go through more changes during the early years of childhood. The process of prenatal development occurs in three main stages. The first two weeks after conception are known as the germinal stage, the third through the eighth week is known as the embryonic period, and the time from the ninth week until birth is known as the fetal period.
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Reactions of Alkyl halides
In this type of reaction, a nucleophile reacts with haloalkane (the substrate) having a partial positive charge on the carbon atom bonded to halogen. A substitution reaction takes place and halogen atom, called leaving group departs as halide ion. Since the substitution reaction is initiated by a nucleophile, it is called nucleophilic substitution reaction
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Substitution and Elimination Electron Flow Pathway
Path Limitations There are three requirements for the S N 2 reaction. In order to be pushed out, the leaving group must be at least fair, usually good. The nucleophile also must be reactive enough to push out the leaving group. Finally, the back side of the tetrahedral carbon attacked must be accessible to the nucleophile and not blocked by other groups.
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The SN2 reaction
The hydroxide ion is a good nucleophile since the oxygen atom has a negative charge and a pair of unshared electrons. The carbon atom is electrophilic since it is bound to a (more electronegative) halogen, which pulls electron density away from the carbon, thus polarizing the bond with carbon bearing partial positive charge and the halogen bearing partial negative charge. The nucleophile is attracted to the electrophile by electrostatic charges. The nucleophile attacks the electrophilic carbon through donation of 2 electrons. Carbon can only have a maximum of 8 valence electrons, so as the carbon nucleophile bond is forming, then the carbon-leaving group bond must be breaking. Iodide is the leaving group since it leaves with the pair of electrons that once bound it to carbon.
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